Jobim 2008

نویسندگان

  • Pierre Blavy
  • Florence Gondret
  • Hervé Guillou
  • Sandrine Lagarrigue
  • Pascal Martin
  • Ovidiu Radulescu
  • Anne Siegel
  • Jaap Van Milgen
چکیده

We propose a modelling strategy to determine from a large set of reactions the smallest set necessary to be compatible with a compendium of required properties and experimental data. We applied this strategy to define a model of hepatic fatty acid metabolism integrating both metabolic pathways and the contribution of some major genetic regulators. We considered the fatty acid metabolism in hepatic cells of mice during a 72 hours fed-to-fast transition and we tested the key role of oxidation and elongation in fatty acid metabolism

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Natural killer cells and immune surveillance.

OBJECTIVES To analyze the importance of natural killer cells, their killer immunoglobulin-like receptors (KIR) and genes in autoimmunity and in the immune surveillance against infectious agents and stem cells transplantation. The characteristics and polymorphisms of the KIR genes and receptors in the Brazilian population is described. SOURCES Textbooks, review articles and recent scientific a...

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تاریخ انتشار 2008